The Binding of Isaac: Rebirth

"When Isaac’s mother starts hearing the voice of God demanding a sacrifice be made to prove her faith, Isaac escapes into the basement, where he faces droves of deranged enemies, lost brothers and sisters, his fears and eventually his mother.

Gameplay
The Binding of Isaac: Rebirth is the randomly generated action RPG shooter that started the new roguelike era. Following Isaac on his journey, players will find bizarre treasures that change Isaac’s form, giving him superhuman abilities and enabling him to battle droves of mysterious creatures, discover secrets and fight his way to safety.

Key Features:
Over 500 hours of gameplay
4 BILLION Seeded runs!
20 Challenge runs
450+ items
Integrated controller support for popular control pads
Analog directional movement and speed
Tons of feature film-quality animated endings
Over 100 specialized seeds
2-player local co-op
Over 100 co-op characters
Dynamic lighting, visual effects and art direction
Multiple Save slots
Poop physics!
A bunch of achievements
The ultimate roguelike

Uber secrets including:
10 Playable Characters
100+ enemies
Over 50 bosses
Mystic Runes
Upgradeable shops
Rooms FULL OF POOP!"

Added touch-screen touch-areas for the Tainted Cain and Tainted Isaac Inventory cycling.
Fixed a bug where the virtual sticks would not fade out if touches were active when the app is suspended and then resumed.
Fixed issue where two active/pocket items were triggered.
Virtual sticks on iOS now render over the left/right letterbox bars.
Fixed issue BOIOS-82 - Tainted Cain can't activate his pocket items
Fixed issue BOIOS-83 - Tainted ??? poop bombs not useable
Fixed issue BOIOS-84 - Jacob and Esau double pill/card use
Fixed issues with Pocket Items for Tainted Judas, Cain, and Eve, and other characters.
Fixed keyboard support for Mac Catalyst.
Fixed an issue with the save data in Mac Catalyst.
Fixed some bugs related to the Device ID on iOS and Mac Catalyst.
Added touch button to switch Forgotten and Soul for Repentance and AB+.
Fixed a crash bug in the video player.
Fixed a bug in the leaderboard display, showing too many entries per page.